Endocrine Abstracts

Background: This study was planned to reveal the effect of propylthiouracil treatment on CD40, hs-CRP and Fetuin-A levels of subjects with subclinical hyperthyroidism.Material and methods: After checking CD40, hs-CRP and Fetuin-A levels of 35 patients with subclinical hyperthyroidism, they were given 50 mg of propylthiouracil tablet (thrice daily). After the 3-month administration, CD40, hs-CRP and Fetuin-A levels were then compared to the levels before ...

Background: The objective of this trial is to determine pre- and post-levothyroxine treatment levels of inflammation markers, high sensitive-C reactive protein (hs-CRP) and fetuin A in cases with subclinical hypothyroidism.Material and methods: A total of 32 patients with a diagnosis of subclinical hypothyroidism and a control group of 30 healthy individuals were tested for hs-CRP ile fetuin A levels, followed by administration of 50 μg levothyroxin...

Introduction: Common polymorphisms of the fat mass and obesity associated gene (FTO) is known to associate with increased obesity and diabetes mellitus type 2. This was the first study to investigate the association between the rs9939609 FTO gene polymorphism and gestational diabetes mellitus (GDM) in Turkish women.Patients and methods: The case-control study included 203 gestational diabetes and 191 non-diabetic pregnant controls. Anthropometric and bio...

Introduction: 46 XX male syndrome generally presented as hypogonadotrophic hypogonadism.Case report: A 39-year-old man was referred to our clinic with a pituitary mass. He had a history of pituitary adenoma of 45×28×40 mm size which was found after his admission with right-sided vision loss at 2006. The hormonal analyses showed hypogonadotrophic hypogonadism without any excess hormone levels. A transcranial pituitary adenomectomy was performed....

Background: Fahr’s disease is a rare degenerative disorder characterized by symmetrical and bilateral intracranial calcification. Movement disorders are the most common symptoms of Fahr’s disease and dystonia is an uncommon presentation which accounts for only 8% of symptomatic patients.Case report: A 47 years old female admitted to emergency department with involuntary movements of extremities and anxiety. Neurological examination was normal e...

The combination of acute pancreatitis (AP), severe hypertriglyceridemia (HTG), and diabetic ketoacidosis (DKA) possess a life-threatening triad. The pathogenesis of HTG is explained by insulin deficiency, but although DKA is a frequent complication in children and adolescents, this triad is rare. We report a 10-year-old girl with Type 1 Diabetes Mellitus (DM) for 10 months, who presented with DKA, severe HTG and AP. Her serum was lipemic. She had HTG (1733 mg/dL) and severe ab...

Introduction: Pseudohypoparathyroidism (PHP) is a rare disease characterized by end-organ resistance to parathyroid hormone, causing hypocalcemia with hyperphosphatemia and elevated parathormone (PTH) levels. A prevalence of 3.4/million has been reported. Here, we present a rare case with PHP.Case report: A 28-year-old male patient with spasms in hands and feet was evaluated in the outpatient department of neurology and was referred to endocrinology clin...

Introduction: Atypical parathyroid adenoma (APA) is a difficultly diagnosed tumor, including some histological features of parathyroid carcinoma (PC). In literature, no definite criteria are considered to be present to distinguish preoperatively APA from PC. It is difficult to distinguish APA and PC intraoperatively. Our report, a case applying with high levels of calcium (Ca) and intact parathyroid hormone (iPTH) and diagnosed with APA was presented.Cas...

Introduction: Dyskeratosis congenita is a rare multisystemic disease characterised with atrophy on skin, pigmentation, nail dystrophy, leukoplakia in mucous membrane, bone marrow failure, and tendency to malignancy. We present a rare case of dyskeratosis congenita associated with hypothyroidism and hypogonadism.Case: A 30-year-old male patient was referred to Endocrinology Department with the findings of micropenis and atrophic testicles. His parents had...